I've run 416's on Deerslayer since '98 with onboard air for easy adjustment even while rolling. Don't have any rebound damping but do have a large sweet spot provided you match the preload accurately to the load. Makes for the cushiest ride possible IMHO.
I've done the same with my second I/S, and used the compressor from a GL1200A on a custom mount inside the fairing. A remote electric pressure gauge plus handlebar-mounted controls for the fill/bleed solenoid valves and compressor run functions round everything out.
You can increase their load capacity by adding extra ATF fluid in them. (That gem was provided on the down-low by their tech guy Jorge years ago - undocumented feature and they will deny it.)
Filed for future reference.

They are useful if your load changes dramatically - easy adjustment esp. with onboard air.
I don't have a trunk on the I/S at the moment, but I have carried passengers up to 200lbs with this setup. For solo riding I find 55-65PSI works great for a "taut" ride, and 75PSI while riding 2-up gives a nice, cushy ride that doesn't bottom out over the average road surface. (I tend to ride a little more sanely with a passenger aboard, so I don't care if the bike loses a little sportiness in the rear with these shocks when they're run near their max ratings.)
However they need to be rebuilt periodically.
-and-
And they do develop leaks and need the seals replaced. Which you can get the kit and do yourself - still an unnecessary hassle if you ask me.
This summer I'll have 12 years on mine, though not quite that many thousands of miles. What's the max air pressure you run in yours, in light of:
But I also have the onboard air which exceeds their recommended pressure so I could have abused them.
When I set up Valk #2 I instead went to premium Prog. 444's with carefully matched springs and damper. On this bike I have occasional co-riders and regularly tow trailers which I set up with plenty of tongue weight for good tracking. With careful spring match these shocks work better for me. I rarely - read, never - change the preload - run it on max all the time.
My 'Valk #2' is a Tourer w/ the I/S's trunk, a Memphis Batwing and other touring accessories added. It currently runs the I/S's OEM shocks and these have around 28K miles on them at the moment. I'm around 230lbs in gear, and may have another 230lbs in passenger and gear aboard the bike at times. What would be a good 444 setup to use in this application?