In the past I have used Gumout Regain as a carb cleaner. Used it going west this yr. Regain is suppose to increase MPG. And it does. I normally get 32 mpg. Used regain and get 38 mpg. Its constant for the 1st 300 miles or so then it slowly drops back to 32 mpg after 5-600 miles. So how does it work? And why dont it stay at 38 mpg? Something I wondered for awhile.

Ive had a similar experience when using Techron a full bottle to 5 gallons of gas in any bike.
Or in my Z 28 a bottle for every 20 gallons of fuel.
In the car on the higway.
Mileage will increase from its normal 21 mpg to almost 28 for the same speed and distance.
I believe that the additives make the gasoline burn more effectively.
Chevron adds techron at the pump but in much smaller per gallon amounts.
As a mileage booster both products do work and work well.
But it is NOT cost effective per gallon to achieve it.
Its cost per gallon simply doesnt justify its use every tankfull.
Of course your not going to get the mileage benifit once its been consumed.
But you will have a cleaner bunch of carbs which in itself should increase your mileage a bit.